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PRF EZ Gel Natural Rejuvenation offered in Cleveland, OH at CPSI Med Spa

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If you’re looking for a state-of-the-art, natural skin rejuvenation treatment in Cleveland, OH, PRF EZ Gel may be exactly what you need. At Cleveland Plastic Surgery Institute Med Spa, we offer this advanced injectable solution to help patients achieve a smoother, more youthful appearance.

PRF EZ Gel combines the regenerative power of your own blood with the science of biostimulation, creating a long-lasting, natural volumizer for the face. Think of it as your body’s own filler—stimulating collagen, improving texture, and restoring lost volume, all while enhancing your skin’s overall health.

What Is PRF EZ Gel?

PRF stands for Platelet-Rich Fibrin, a second-generation platelet concentrate made from your own blood. EZ Gel is a heat-treated version of PRF that thickens the consistency into a gel, creating a more stable, longer-lasting injectable. When combined, PRF EZ Gel offers both immediate volume and long-term rejuvenation.
PRF EZ Gel is 100% autologous, meaning it’s derived entirely from your body. There are no additives, making it an ideal option for patients who prefer natural alternatives.

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Benefits of PRF EZ Gel Treatment

Why are more patients in Cleveland choosing PRF EZ Gel at CPSI Med Spa? Here are just a few of the benefits:

  • All-natural rejuvenation – no chemicals, no foreign substances
  • Stimulates collagen production for smoother, firmer skin
  • Reduces fine lines and wrinkles over time
  • Improves skin tone, texture, and elasticity
  • Restores volume in cheeks, under eyes, nasolabial folds, and other areas
  • Minimal risk of allergic reaction or inflammation
  • Gradual, natural-looking results that continue to improve over weeks and months
  • Customizable for your individual skin concerns
  • All-natural rejuvenation – no chemicals, no foreign substances
  • Stimulates collagen production for smoother, firmer skin
  • Reduces fine lines and wrinkles over time
  • Improves skin tone, texture, and elasticity
  • Restores volume in cheeks, under eyes, nasolabial folds, and other areas
  • Minimal risk of allergic reaction or inflammation
  • Gradual, natural-looking results that continue to improve over weeks and months
  • Customizable for your individual skin concerns

PRF EZ Gel is ideal for those who want to age gracefully using regenerative techniques rather than artificial fillers.

PRF EZ Gel is ideal for those who want to age gracefully using regenerative techniques rather than artificial fillers.

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Who Is a Good Candidate for PRF EZ Gel?

Most healthy adults are good candidates for PRF EZ Gel. It’s especially beneficial for individuals who:

  • Prefer natural treatments with minimal additives
  • Want subtle, gradual facial rejuvenation
  • Are looking to smooth wrinkles, fill hollow areas, or improve skin quality
  • Have early signs of aging or skin thinning


Since PRF EZ Gel is made using your own blood, it’s safe for nearly everyone. However, it may not be suitable for patients with certain blood disorders or who are taking anticoagulants. During your consultation at Cleveland Plastic Surgery Institute Med Spa, we’ll help you determine if this treatment is right for you.

How PRF EZ Gel Works
The Science Behind It

PRF is obtained by drawing a small amount of your blood and spinning it in a low-speed centrifuge. This separates the platelet-rich layer, which is full of healing growth factors. When heated to a controlled temperature, this PRF transforms into a gel-like substance that holds its shape when injected.

Here’s what you can expect during a PRF EZ Gel appointment at our Cleveland Med Spa:

We evaluate your skin, review your goals, and determine the best injection sites.

A small vial of blood is drawn from your arm—similar to a routine lab test.

The blood is spun to isolate the PRF.

The PRF is gently heated to create the gel consistency.

The heated gel is blended with the remaining liquid PRF using a dual-syringe system. This creates a smooth, injectable material rich in growth factors and platelets.

The gel is carefully injected into targeted areas of your face, such as under the eyes, cheeks, or smile lines.

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The entire procedure typically takes less than an hour, and most patients return to normal activities the same day.

Unsure? PRF EZ Gel Book a consultation at our
Cleveland office to find out if PRF is right for you.

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What to Expect After Treatment

PRF EZ Gel requires little to no downtime. You may experience swelling, redness, or tenderness at the injection sites, which typically resolves within a week.


Recovery Tips:

  • Avoid vigorous exercise for 24 to 48 hours
  • Keep skin clean and avoid heavy makeup the day of treatment
  • Apply ice packs as needed for comfort
  • Stay hydrated to support healing


Your results will develop gradually over 4–6 weeks as your skin begins to rebuild collagen. Unlike traditional fillers that show instant results but wear off quickly, PRF EZ Gel promotes long-lasting, more natural improvements over time.

Results of PRF EZ Gel

Patients often report:

  • Plumper, healthier-looking skin
  • Diminished under-eye hollows
  • Smoother smile lines and marionette folds
  • Improved skin tone and radiance


Most people notice visible improvement within the first month, with continued enhancement for 3–6 months.
We often recommend a series of two to three treatments for optimal results, spaced 4–6 weeks apart. Maintenance sessions can be done once or twice per year depending on your skin goals.

Unsure? PRF EZ Gel Book a consultation at our
Cleveland office to find out if PRF is right for you.

BOOK A CONSULTATION

Why Choose Cleveland Plastic Surgery Institute Med Spa?

At CPSI Med Spa, we’re proud to offer the latest advancements in regenerative medicine under the direction of board-certified plastic surgeon Dr. Jason Leedy. Our team is extensively trained in PRF-based therapies and aesthetic injectables, ensuring your results are safe, effective, and beautiful.
We focus on:

  • Personalized treatment plans tailored to your skin needs
  • Natural-looking outcomes that highlight your features
  • A relaxing, professional med spa environment
  • Honest advice on what treatments are best for you

We’re conveniently located in Cleveland, OH, and serve patients throughout Northeast Ohio.

Related Treatments You May Be Interested In

Explore other regenerative and non-surgical options available at our Med Spa:

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