PRF Treatment Offered in Cleveland, OH

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1,300+ 5-Star Reviews for Cleveland Plastic Surgery Institute and its providers

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At Cleveland Plastic Surgery Institute Med Spa, we believe that the most powerful tools for rejuvenation come from within. Our PRF treatment in Cleveland, OH (Platelet-Rich Fibrin) is a cutting-edge, natural option for patients looking to restore youthful skin, brighten under-eye circles, or combat thinning hair—all without surgery.

Conveniently located in Mayfield Heights, our practice brings world-class aesthetic care to the greater Cleveland area, offering you advanced regenerative solutions that align with your body’s natural healing process.

What Is PRF &
How Does It Work?

Platelet-Rich Fibrin (PRF) is a next-generation regenerative treatment derived entirely from your own blood. Unlike PRP (Platelet-Rich Plasma), PRF is processed without anticoagulants and spun at a lower speed, preserving more healing components such as platelets, white blood cells, stem cells, and growth factors.

Here’s how it works:

  • We draw a small sample of your blood right here in our Cleveland med spa.
  • It’s spun in a specialized centrifuge to isolate the PRF layer.
  • This layer is then injected or applied to the treatment area—face, scalp, or under eyes.
  • Over the next several weeks, PRF promotes collagen production, cell regeneration, and tissue healing.

This slow, sustained release of growth factors sets PRF apart from other treatments.

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The Benefits of PRF Treatment

PRF EZ Gel

Why Cleveland Patients Choose PRF Treatment

Patients across Northeast Ohio are discovering the benefits of PRF therapy for skin rejuvenation and hair restoration. At Cleveland Plastic Surgery Institute Med Spa, PRF is a patient favorite because it offers:

  • Completely natural and biocompatible treatment
  • Minimal downtime or discomfort
  • Safe for all skin types
  • Subtle, long-lasting rejuvenation

Whether you’re prepping for a big event or simply want to refresh your look, PRF can help you glow from the inside out.

PRF vs PRP:
What’s the Difference?

Though both PRP and PRF use your own blood to stimulate healing, PRF has clear advantages:

Platelet-Rich Plasma

Also Known As PRP

Additives

Uses anticoagulants

Spin Speed

High

Growth Factor Release

Fast, short-term

Healing Potential

Moderate

Platelet-Rich FIBRIN

Also Known As PRF

Additives

None (100% natural)

Spin Speed

Low (preserves more healing cells)

Growth Factor Release

Slow, sustained over 7+ days

Healing Potential

Higher concentration of stem cells and platelets

Our Cleveland-based providers recommend PRF to patients seeking a longer-lasting , more natural effect than traditional PRP.

What Conditions Can PRF Treat?

Though both PRP and PRF use your own blood to stimulate healing, PRF has clear advantages:

Facial Rejuvenation

PRF can smooth fine lines, improve skin texture, and restore volume in areas like:

  • Smile lines
  • Crow’s feet
  • Forehead wrinkles
  • Acne scarring

Hair Restoration

Thinning at the crown or temples? PRF stimulates hair follicles and increases blood flow to the scalp, leading to:

  • Increased hair thickness
  • Reduced hair shedding
  • Stronger, healthier follicles

Under-Eye Rejuvenation

If you suffer from dark circles or under-eye hollowness, PRF provides a gentle, effective solution—without the risks sometimes associated with fillers.

We specialize in non-surgical hair restoration for both men and women in the Cleveland area.

What to Expect from Your
PRF Treatment in Cleveland

Your experience at our med spa is designed for comfort, safety, and results.

Step-by-Step Process:

You’ll meet with one of our experienced providers to discuss your goals and create a personalized treatment plan.

We collect a small blood sample:

The blood is processed onsite in our medical-grade centrifuge.

PRF is applied to your face or injected into precise areas like the scalp or under-eyes.

Mild redness or swelling may occur but typically resolves within 24–48 hours.

PRF EZ Gel

How Many PRF Treatments Will I Need?

We generally recommend a series of 3–4 treatments spaced 4–6 weeks apart for optimal results. Maintenance sessions every 6–12 months help keep your skin and hair looking their best.
Your provider at Cleveland Plastic Surgery Institute Med Spa will customize a plan tailored to your skin type, age, and goals.

Is PRF safe?

Yes. PRF is completely natural, made from your own blood, and free of foreign substances. That’s why our Cleveland patients love it—it’s regenerative skincare at its purest.
No risk of allergic reaction. Just your body doing what it does best: heal and regenerate.

Who’s a Good Candidate for PRF?

You’re likely a great fit for PRF if you:

  • Prefer natural alternatives to fillers or surgery
  • Have under-eye hollows, fine lines, or thinning hair
  • Want rejuvenation without downtime
  • Are in good general health

Unsure? Book a consultation at our
Cleveland office to find out if PRF is right for you.

Aftercare Tips

To protect your results:

  • Avoid strenuous activity for 24 to 48 hours
  • Refrain from touching or washing treated areas immediately
  • Apply sunscreen and avoid direct sun exposure
  • Follow your provider’s skincare recommendations

We provide detailed aftercare instructions to every patient so you can heal quickly and comfortably.

PRF Treatment Combinations

PRF can be combined with other in-office treatments for even greater results:

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PRF Hair Supplements

The most frequently asked questions
about PRF

 You can expect results to last 6–12 months. Many patients maintain results with annual touch-ups.

Discomfort is minimal. We use numbing cream to ensure a comfortable experience.

You may notice initial improvements within 2–3 weeks, with full results developing over 2–3 months.

 It depends on your goals. PRF offers subtle, natural results with long-term collagen stimulation. Filler offers more immediate volume. We’ll help you decide what’s best during your consultation.

Top Reviewed Plastic Surgeon in Cleveland

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